Literature / Clinical trials

wIRA superficial HT

Vaupel P, Piazena H, Müller W, Notter M:
Biophysical and photobiological basics of water-filtered infrared-A hyperthermia of superficial tumors.
Int J Hyperthermia. 2018 May 10:1-11. doi: 10.1080/02656736.2018.1469169. [Epub ahead of print]
https://www.tandfonline.com/doi/full/10.1080/02656736.2018.1469169

Notter M, Vaupel P
Re-irradiation and wIRA-hyperthermia for superficial widespread breast cancer recurrences: an up-date
ESHO Congress 2017 Athen, Oral presentation, Abstract OP-04

Thomsen AR, Aldrian C, Heselich A, Niedermann G, Grosu AL, Lund PG
Hyperthermia with water-filtered infrared A sensitizes breast cancer spheroids to hypofractionated irradiation, but not normal epidermal cell cultures
ESHO Congress 2017 Athen, Poster presentation, Abstract PP-25
http://www.esho2017.eu/articlefiles/FINAL%20ABSTRACT%20BOOK%20VS2.pdf

Notter M, Piazena H, Vaupel P:
Hypofractionated re-irradiation of large-sized re-current breast cancer with thermography-controlled, contact-free water-filtered infrared-A hyperthermia: A retrospective study of 73 patients.
International Journal of Hyperthermia Volume 33, 2017 - Issue 2, pp. 227-236
OPEN ACCESS http://www.tandfonline.com/doi/full/10.1080/02656736.2016.1235731

Dombrovsky LA, Timchenko V, Pathak C, Piazena H, Müller W, Jackson M:
Radiative heating of superficial human tissues with the use of water-filtered infrared-A radiation: A computational modeling.
International Journal of Heat and Mass Transfer 85 (2015) 311–320
http://www.sciencedirect.com/science/article/pii/S0017931015001519

Stutz E, Puric E, Datta NR, Bodis S, Notter M:
Radiation-Associated Angiosarcoma of the Breast - What can we learn from  case reports?
Strahlenassoziiertes Angiosarkom der Brust - Was können wir aus Fallberichten lernen?
InFo ONKOLOGIE & HÄMATOLOGIE 2017; Vol. 5, Nr. 4
OPEN ACCESS after free registration
[Article in German] https://www.medizinonline.ch/artikel/was-koennen-wir-aus-fallberichten-lernen

Seegenschmiedt MH, Klautke G, Walther E, Feldmann HJ, Katalinic A, Stuschke M, von Lieven H, Vaupel P:
Water-filtered infrared-A-hyperthermia combined with radiotherapy in advanced and recurrent tumors. Initial results of a multicenter phase I-II study.
Strahlenther Onkol. 1996 Sep;172(9):475-84.
[Article in German] https://www.ncbi.nlm.nih.gov/pubmed/8928056

Vaupel P, Kelleher DK, Krüger W:
Water-filtered infrared-A radiation: a novel technique to heat superficial tumors
Strahlenther Onkol. 1992 Nov; 168(11):633-9
https://www.ncbi.nlm.nih.gov/pubmed/1455291

Thermography in superficial HT

Müller J, Hartmann J, Bert C
Infrared camera based thermometry for quality assurance of superficial hyperthermia applicators.
Phys Med Biol. 2016 Apr 7;61(7):2646-64
https://www.ncbi.nlm.nih.gov/pubmed/26976046

Reviews on combined RT/HT of locally recurrent breast cancer

Datta NR, Puric E, Klingbiel D, Gomez S, Bodis S
Hyperthermia and Radiation Therapy in Locoregional Recurrent Breast Cancers: A Systematic Review and Meta-analysis.
Int J Radiat Oncol Biol Phys. 2016 Apr 1;94(5):1073-87.
https://www.ncbi.nlm.nih.gov/pubmed/26899950

Maluta S, Kolff MW:
Role of Hyperthermia in Breast Cancer Locoregional Recurrence: A Review.
Breast Care (Basel). 2015 Dec;10(6):408-12. doi: 10.1159/000440792. Epub 2015 Oct 16. Review.
OPEN ACCESS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789878/

Kouloulias V, Triantopoulou S, Uzunoglou N, Pistevou-Gompaki K, Barich A, Zygogianni A, Kyrgias G, Kardamakis D, Pectasidis D, Kouvaris J:
Hyperthermia is now included in the NCCN Clinical Practice Guidelines for Breast Cancer Recurrences: An analysis of existing data
Breast Care 2015, 10:109-116
https://www.karger.com/Article/FullText/376594

Zagar TM, Oleson JR, Vujaskovic Z, Dewhirst MW, Craciunescu OI, Blackwell KL, Prosnitz LR, Jones EL:
Hyperthermia combined with radiation therapy for superficial breast cancer and chest wall recurrence: a review of the randomised data.
Int J Hyperthermia. 2010;26(7):612-7.
OPEN ACCESS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956421/

Datta NR, Ordóñez SG, Gaipl US, Paulides MM, Crezee H, Gellermann J, Marder D, Puric E, Bodis S:
Local hyperthermia combined with radiotherapy and-/or chemotherapy: Recent advances and promises for the future.
Cancer Treat Rev. 2015 Nov;41(9):742-53 https://www.ncbi.nlm.nih.gov/pubmed/26051911

Trials /analyses on combined RT/HT of locally recurrent breast cancer

Randomised trials

Jones EL, Oleson JR, Prosnitz LR, Samulski TV, Vujaskovic Z, Yu D, Sanders LL, Dewhirst MW:
Randomized trial of hyperthermia and radiation for superficial tumors.
J Clin Oncol. 2005 May 1;23(13):3079-85.
OPEN ACCESS http://ascopubs.org/doi/abs/10.1200/jco.2005.05.520

Vernon CC, Hand JW, Field SB, Machin D, Whaley JB, van der Zee J, van Putten WL, van Rhoon GC, van Dijk JD, González González D, Liu FF, Goodman P, Sherar M:
Radiotherapy with or without hyperthermia in the treatment of superficial localized breast cancer: results from five randomized controlled trials. International Collaborative Hyperthermia Group.
Int J Radiat Oncol Biol Phys. 1996 Jul 1;35(4):731-44.
https://www.ncbi.nlm.nih.gov/pubmed/8690639

Non randomised trials / retrospective analyses

Oldenborg S, Valk C, van Os R, Oei B, Venselaar J, Vörding PZ, van Randen A, Crezee H, van Tienhoven G, Rasch C
Rib fractures after reirradiation plus hyperthermia for recurrent breast cancer: Predictive factors.
Strahlenther Onkol. 2016 Apr;192(4):240-7
OPEN ACCESS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833788/

Auoragh A, Strnad V, Ott OJ, Beckmann MW, Fietkau R:
Re-irradiation of the chest wall for local breast cancer recurrence : Results of salvage brachytherapy with hyperthermia.
Strahlenther Onkol. 2016 Sep;192(9):617-623.
https://www.ncbi.nlm.nih.gov/pubmed/27381751

Oldenborg S, Griesdoorn V, van Os R, Kusumanto YH, Oei BS, Venselaar JL, Zum Vörde Sive Vörding PJ, Heymans MW, Kolff MW, Rasch CR, Crezee H, van Tienhoven G:
Reirradiation and hyperthermia for irresectable locoregional recurrent breast cancer in previously irradiated area: Size matters.
Radiother Oncol. 2015 Nov;117(2):223-8
https://www.ncbi.nlm.nih.gov/pubmed/26542015

Datta NR, Puric E, Heuberger J, Marder D, Lomax N, Timm O, Memminger P, Bodis S:
Hyperthermia and reirradiation for locoregional recurrences in preirradiated breast cancers: a single institutional experience.
Swiss Med Wkly. 2015;145:w14133
OPEN ACCESS https://smw.ch/article/doi/smw.2015.14133

Linthorst M, Baaijens M, Wiggenraad R, Creutzberg C, Ghidey W, van Rhoon GC, van der Zee J:
Local control rate after the combination of re-irradiation and hyperthermia for irresectable recurrent breast cancer: Results in 248 patients.
Radiother Oncol. 2015 May 19.
https://www.ncbi.nlm.nih.gov/pubmed/26002305

Refaat T, Sachdev S, Sathiaseelan V, Helenowski I, Abdelmoneim S, Pierce MC, Woloschak G, Small W Jr, Mittal B, Kiel KD:
Hyperthermia and radiation therapy for locally advanced or recurrent breast cancer.
Breast. 2015 Aug;24(4):418-25.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791303/

Harms W, Geretschläger A, Cescato C, Buess M, Köberle D, Asadpour B:
Current Treatment of Isolated Locoregional Breast Cancer Recurrences.
Breast Care (Basel). 2015 Aug;10(4):265-71.
OPEN ACCESS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608638/

Trujillo-Romero CJ, Paulides MM, Drizdal T, van Rhoon GC:
Impact of silicone and metal port-a-cath implants on superficial hyperthermia treatment quality.
Int J Hyperthermia. 2014 Dec 12:1-8.
https://www.ncbi.nlm.nih.gov/pubmed/25495267

Müller AC, Eckert F, Heinrich V, Bamberg M, Brucker S, Hehr T:
Re-surgery and chest wall re-irradiation for recurrent breast cancer: a second curative approach.
BMC Cancer. 2011 May 25;11:197.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125280/

Van Der Zee J, De Bruijne M, Mens JW, Ameziane A, Broekmeyer-Reurink MP, Drizdal T, Linthorst M, Van Rhoon GC:
Reirradiation combined with hyperthermia in breast cancer recurrences: overview of experience in Erasmus MC.
Int J Hyperthermia. 2010;26(7):638-48.
https://www.ncbi.nlm.nih.gov/pubmed/20849259

Zagar TM, Oleson JR, Vujaskovic Z, Dewhirst MW, Craciunescu OI, Blackwell KL, Prosnitz LR, Jones EL:
Hyperthermia for locally advanced breast cancer.
Int J Hyperthermia. 2010;26(7)
OPEN ACCESS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949291/

Combined RT/HT of radio-induced angiosarcoma

Depla AL, Scharloo-Karels CH, de Jong MA, Oldenborg S, Kolff MW, Oei SB, van Coevorden F, van Rhoon GC, Baartman EA, Scholten RJ, Crezee J, van Tienhoven G:
Treatment and prognostic factors of radiation-associated angiosarcoma (RAAS) after primary breast cancer: a systematic review.
Eur J Cancer. 2014 Jul;50(10):1779-88.
https://www.ncbi.nlm.nih.gov/pubmed/24731859

Linthorst M, van Geel AN, Baartman EA, Oei SB, Ghidey W, van Rhoon GC, van der Zee J:
Effect of a combined surgery, re-irradiation and hyperthermia therapy on local control rate in radio-induced angiosarcoma of the chest wall.
Strahlenther Onkol. 2013 May;189(5):387-93.
https://www.ncbi.nlm.nih.gov/pubmed/23549781

Combined RT/HT of malignant melanoma

Overgaard J, Gonzalez Gonzalez D, Hulshof MC, Arcangeli G, Dahl O, Mella O, Bentzen SM:
Randomised trial of hyperthermia as adjuvant to radiotherapy for recurrent or metastatic malignant melanoma. European Society for Hyperthermic Oncology.
Lancet. 1995 Mar 4;345(8949):540-3.
https://www.ncbi.nlm.nih.gov/pubmed/7776772

Comment:
Overgaard J, Gonzalez Gonzalez D, Hulshof MC, Arcangeli G, Dahl O, Mella O, Bentzen SM:
Hyperthermia as an adjuvant to radiation therapy of recurrent or metastatic malignant melanoma. A multicentre randomized trial by the European Society for Hyperthermic Oncology. 1996.
Int J Hyperthermia. 2009 Aug;25(5):323-34.
https://www.ncbi.nlm.nih.gov/pubmed/19670088

Other selected publications on HT and RT

Peeken JC, Vaupel P, Combs SE:
Integrating Hyperthermia into Modern Radiation Oncology: What Evidence Is Necessary?
Review ARTICLE
Front Oncol. 2017 Jun 30;7:132
OPEN ACCESS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492395/

Oei AL, Vriend LE, Crezee J, Franken NA, Krawczyk PM:
Effects of hyperthermia on DNA repair pathways: one treatment to inhibit them all.
Radiat Oncol. 2015 Aug 7;10:165
OPEN ACCESS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554295/

Vaupel P, Kelleher DK:
Pathophysiological and vascular characteristics of tumors and their importance for hyperthermia: heterogeneity ist the key issue.
Int J Hyperthermia 2010; 26(3):211-223
https://www.ncbi.nlm.nih.gov/pubmed/20345270

van der Zee J, Vujaskovic Z, Kondo M, Sugahara T:
The Kadota Fund International Forum 2004 - clinical group consensus.
Int J Hyperthermia. 2008 Mar;24(2):111-22.
OPEN ACCESS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759185/

Horsman MR, Overgaard J:
Hyperthermia: A potent enhancer of radiotherapy.
Clin Oncol (R Coll Radiol),2007, 19:418-426
https://www.ncbi.nlm.nih.gov/pubmed/17493790

Dewhirst MW, Vujaskovic Z, Jones E, Thrall D:
Re-setting the biologic rationale for thermal therapy.
Int J Hyperthermia. 2005 Dec;21(8):779-90
https://www.ncbi.nlm.nih.gov/pubmed/16338861